PW51: Current Research with MDMA

Pharmacy Webinar 51


Current Research with MDMA

with Natalie Metz, ND, MA

TUESDAY, January 25, 2022
: 6:30 - 8:30pm

2 pharmacy CEs* (approved by CNDA; pending approval by OBNM)

2 CEs for CA LAc* (pending)

REGISTER NOW * $75 members  |  $95 non-members

3,4-methylenedioxy-methamphetamine (MDMA) is a unique psychoactive substance known for its euphoric, empathogenic, and psychostimulant effects. It has been explored in psychotherapeutic contexts for over thirty years, having been first introduced to the therapeutic community by the pioneering psychedelic chemist Alexander “Sasha” Shulgin in the San Francisco Bay Area.
MDMA’s utility as a catalyst for transformative therapeutic work was recognized early on, and it was introduced to thousands of therapists who supported their patients’ growth and healing with psychotherapy-assisted MDMA sessions before it was placed in Schedule I by the DEA in 1985.
This scheduling of MDMA made it illegal to possess or utilize, and effectively ended all above ground therapeutic work, despite many efforts by clinicians and patients to advocate for its potential benefit.
In 1986, Rick Doblin formed the Multidisciplinary Association for Psychedelic Studies (MAPS), a non-profit research and educational organization that develops medical, legal, and cultural contexts to explore careful uses of psychedelics and cannabis.
In 2010, MAPS published the first randomized, controlled pilot study looking at the safety and efficacy of MDMA-assisted psychotherapy for patients with chronic, treatment-resistant posttraumatic stress disorder (PTSD), demonstrating excellent results. MDMA was granted “breakthrough therapy designation” by the FDA in 2017 and has continued to be studied in populations with PTSD, anxiety related to terminal illness, and more. These studies continue to demonstrate safety and efficacy, and the long term follow up data has shown lasting benefits after only a few treatments.
MDMA is currently being investigated in Phase 3 clinical trials in the US, and the mechanisms of action by which MDMA imparts its unique therapeutic effects continue to be explored. A review of past and current clinical research, the basic pharmacology of MDMA, and its unique neuromodulatory effects will highlight the therapeutic potentials of this unique molecule, pointing toward the need for more research and clinical applications.
This is the third of a series of webinars which will present an overview of psychedelic-assisted therapies.
Goals and Objectives:

  • After the presentation, participants will be able to confidently:
  • Understand basic neuroscience, pharmacology, and proposed therapeutic mechanisms of action of MDMA
  • Describe basic history of MDMA and use in therapeutic contexts
  • Demonstrate familiarity with past and current clinical trials exploring the therapeutic potentials of MDMA-assisted therapies
  • Review the outcomes of select clinical trials and long term follow up data with case studies, demonstrating the overall safety and efficacy of MDMA-assisted therapies


Category 1 TM Credits
CE Provider #805
310 670 8100
This course is pending approval by The California Acupuncture Board for 2 hours of continuing education
This course will be available as a self study after the date of the live webinar. 
*Refunds not available




Dr. Natalie Metz, ND, is a licensed Naturopathic Doctor, herbalist, and faculty member and mentor at the California Institute of Integral Studies and the School of Consciousness Medicine, where she teaches courses on holistic health and psychedelic medicines. She earned a Doctorate in Naturopathic Medicine at Southwest College of Naturopathic Medicine in 2006, and a Master of Arts in Philosophy, Cosmology, and Consciousness in 2014, as well as a Certificate in Psychedelic Therapies and Research in 2016 at CIIS. She serves on the advisory boards for the Limina Foundation and the MAPS Zendo Project. She has a private practice in Oakland, CA, and Santa Fe, NM, where she assists patients in their wellness with the support of plant medicine, diet and lifestyle counseling, and the integration of beyond-ordinary life experiences. She is a lifelong student of dance, a lover of art, travel, and all things purple, and truly enjoys sharing her passion for life with the world.


Naturopathic Advocates

The CNDA is working to educate state legislative and insurance agencies as well as the public on the benefits of naturopathic medicine. We will continue to build relationships in the naturopathic community in an effort to optimize the impact of the naturopathic doctors in our state.